Pripravili a testovali sa rôzne polyméry s molekulovými odtlačkami (MIP). Ako templát na formovanie molekulových odtlačkov sa použil 1-metyl-2-piperidinoetylester 4-decyloxyfenylkarbámovej kyseliny. Na prípravu MIP sa použili monoméry akrylamid, 4-vinylpyridín a kyselina metakrylová a rozpúšťadlá metanol a acetonitril. Ku každému MIP sa pripravili kontrolné polyméry bez molekulových odtlačkov (NIP). Polyméry sa použili ako sorbenty na extrakciu na tuhej fáze (SPE). V tejto práci sa sledoval vplyv zloženia polymerizačnej zmesi na vlastnosti polymérov, ako sú kapacita a selektivita polymérov. Testoval sa tiež vplyv dĺžky a polohy alkoxy reťazca v molekulách látok štruktúrne podobných molekule použitej ako templát na selektivitu polymérov.
Kľúčové slová: polymér s molekulovými odtlačkami - extrakcia na tuhej fáze - HPLC - deriváty fenylkarbámovej kyseliny.
POSSIBILITY OF USING OF MOLECULAR IMPRINTED POLYMERS ON SORPTION SELECTIVITY OF SOME PHENYL CARBAMIC DERIVATIVES
SUMMARY
Molecularly imprinted polymers were prepared and tested. 1-methyl-2-piperidinoethylester of 2- and 4-decyloxyphenylcarbamic acid was used as template for imprints formation. Acrylamide, 4-vinylpyridine and methacrylic acid as monomers and methanol and acetonitrile as solvents were used. Non-imprinted
polymers (NIP) were prepared for each imprinted polymer. Polymers were used as sorbents for solid-phase extraction (SPE). In this work the influence of polymerization mixture composition on polymer properties, such as capacity and selectivity, were investigated. The influence of alkoxy - chain length and position on the selectivity of polymers was also tested.
Key words: MIP - SPE - HPLC - derivatives of phenylcarbamic acids.
M. LACHOVÁ, J. LEHOTAY, I. SKAČÁNI, J. ČIŽMÁRIK
